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KMID : 0191120070220030577
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Journal of Korean Medical Science
2007 Volume.22 No. 3 p.577 ~ p.579
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Clopidogrel-induced Spontaneous Spinal Epidural Hematoma
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Sung Jae-Hoon
Hong Jae-Taek
Son Byung-Chul
Lee Sang-Won
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Abstract
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The hemorrhagic side effects associated with the use of clopidogrel are within the acceptable range and occur mainly at skin or gastrointestinal sites. We report a case of spontaneous spinal epidural hematoma (SSEH) in a 60-yr-old woman who was treated with clopidogrel for frequent transient ischemic attacks. To our knowledge, this is the second reported case of clopidogrel-induced SSEH. The patient’s symptoms and past history of clopidogrel use suggested the diagnosis and made the procedure proceed quickly to operate SSEH 9 hr after the onset of paraplegia. The outcome was excellent. Therefore, with the popularity of antiplatelet prescription, physicians should keep in mind and urgently treat this unusual but critical side effect.
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KEYWORD
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Antiplatelet Agents, Clopidogrel, Spinal Epidural Hematoma
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